Director Toxicology

Director Toxicology Share Department Development ProQR Therapeutics is a NASDAQ-listed biotechnology company headquartered in Leiden, the Netherlands with an office in and Cambridge, Massachusetts, USA. At ProQR, we are on a mission to edit RNA, treat disease and change lives. A team of 180+ enthusiastic ProQRians from all walks of life and more than 30 different nationalities is committed to pioneering transformative RNA therapies to make a difference in the lives of the communities we serve. Our proprietary Axiomer™ RNA editing technology platform enables the editing of specific single nucleotides in RNA using the cells own editing machinery. Axiomer RNA editing technology harnesses ADAR (Adenosine Deaminase Acting on RNA), a protein which is present in all human cells, to repair G-to-A mutations, modulate protein, and enable protective mutation functions. Axiomer could potentially yield a new class of innovative medicines and treat currently untreatable diseases. By harnessing the power of RNA editing, we aim to create a world where genetics inform your health - but never limit it. To strengthen our Axiomer Unit, we are looking for a Director Toxicology (full-time) to support our Translational Development portfolio. Location: Leiden, NL (on-site). The role: ProQR is looking for an experienced Director Toxicology to join the Translational Development team and to provide scientific and strategic leadership for the nonclinical safety assessment of our pipeline. In this role, you will define and execute toxicology strategies that enable the progression of innovative RNA therapeutics from discovery through clinical development. As Director Toxicology, you will work across multidisciplinary project teams and collaborate closely with external partners to ensure robust, science-driven safety packages that support regulatory submissions worldwide. You will play a key role in shaping development strategies while ensuring studies a...