Tumor-microbiome Interactions Postdoc

- - Amsterdam Functieomschrijving Wet-Lab Postdoc in the Voest Lab (fully funded) - Understanding and targeting the microbiome to enhance immunotherapy response. We are recruiting a highly motivated postdoctoral fellow to join a rapidly expanding microbiome research project. This project aims to better understand the metabolic link between the microbiome and our immune system. The project entails experimental assessment and validation of the functional capacity of individual bacterial species and defined microbial communities to modulate anti-tumor immune responses. This role has a strong in vitro focus, with computational and in vivo experience highly valued. This position also offers excellent academic training alongside unique opportunities to collaborate closely with leading industry partners in the microbiome and immuno-oncology space. The postdoc will be a key contributor to a collaborative, team-driven project within the Voest group at the Netherlands Cancer Institute. The postdoc will be expected to develop novel methodologies to assess the impact of microbiota-derived metabolites on immune function and anti-tumor control. In addition to contributing to a collaborative, team-driven research programme, there will be ample opportunity for the candidate to pursue independent scientific ideas aligned with the broader research goals. The role requires an innovative and critical mind to define key biological questions and design robust experimental strategies to address them. You will: - Spearhead the development of in vitro model systems which will allow you to assess the impact of microbiota-derived metabolites on anti-tumor immunity. - Translate your findings to for example patient-derived organoids and mouse models to define the optimal consortia composition for an anti-tumor immune response. - Collaborate closely with a multidisciplinary team of immunologists, microbiologists, and industry partners to translate findings...